South Carolina Football vs. The ACC
From 1953-1970, the South Carolina football program was a member of the ACC. Primarily because of ugly basketball rivalries with North Carolina and Duke, Carolina left the conference in all sports. With conference realignment causing an ever-changing landscape across college football, the ACC has changed quite a bit since those days, and the Gamecocks have missed out on playing some of the newer teams in the league.
Boston College: Boston College was an independent for most of its football history before joining the Big East in the 1990s and the ACC in the 2000s. This matchup doesn’t seem like a likely one unless the Gamecocks and Eagles get paired together for a bowl game as Boston College has only made one bowl game the last five seasons.
Louisville: Despite being old Metro Conference rivals in basketball, South Carolina football and Louisville football have never played on the gridiron. The main out-of-conference rival for SEC foe Kentucky, Louisville has had a similar football program to South Carolina in recent years, so a bowl game matchup could be in the future.
Syracuse: South Carolina football plays lots of orange on its schedule most seasons (Clemson, Florida, Tennessee, and Auburn), but they’ve never played The Orange. Carolina fans do have a soft spot for the team from New York, though, as Syracuse knocked off Clemson to keep them out of the College Football Playoff in 2017.